How To Mix A Tesmorelin Ipamorelin Blend

How To Mix A Tesmorelin Ipamorelin Blend

How To Mix A Tesmorelin/Ipamorelin Blend

Creating a blend of Tesmorelin and Ipamorelin is a common practice among athletes and bodybuilders looking to optimize growth hormone release while minimizing side effects. The combination takes advantage of each peptide’s unique properties: Tesmorelin (a somatostatin analogue) provides a prolonged suppression of the pituitary’s inhibitory signals, whereas Ipamorelin (a selective ghrelin receptor agonist) stimulates GH secretion with minimal impact on cortisol or prolactin levels.

Below is a step-by-step guide that covers everything from preparing the solution to administering it safely. Always keep in mind that this information is for educational purposes only and should be used responsibly under professional supervision.

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1. Gather Your Materials

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2. Calculate Your Target Dose

The blend is typically administered as a single daily dose that combines both peptides in a ratio that maximizes GH release while keeping side effects low.

1. Determine your total daily dose (TDD)

– Common ranges: 10 µg–20 µg of Tesmorelin and 100 µg–200 µg of Ipamorelin per day, depending on training goals and experience level.

1. Set the blend ratio

– A widely used proportion is 1 part Tesmorelin to 4 parts Ipamorelin by mass.

– For example: 10 µg Tesmorelin + 40 µg Ipamorelin equals a 50 µg total dose.

1. Convert micrograms to milligrams for the vial volumes

– 1 mg = 1000 µg.

– If your desired dose is 10 µg Tesmorelin, you’ll need 0.01 mg from a 5 mg/2 mL vial.

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3. Prepare the Diluent

• Volume: Use enough saline to achieve a final concentration that allows accurate injection in a single syringe (typically 1–3 mL total volume).
• Mixing ratio: If you’re aiming for a 50 µg total dose, dissolve both peptides into 2 mL of saline. This gives a concentration of 25 µg/mL.

4. Draw the Peptides

1. Sterilize the vial caps with an alcohol wipe
2. Insert a 29-gauge needle and draw up the required volume

– For Tesmorelin: Calculate the milliliters needed to obtain your target micrograms (e.g., 0.004 mL for 10 µg from a 5 mg/2 mL vial).

– For Ipamorelin: Similarly, calculate the volume (e.g., 0.04 mL for 40 µg from a 3 mg/1 mL vial).

1. Transfer each peptide into separate syringes to keep track of doses.

5. Mix the Peptides

• Combine the contents of both syringes into a single 2-mL syringe or a small mixing container.
• Gently swirl—do not shake—to avoid foam and ensure homogenous distribution.
• Label the mixture with date, time, and total dose for reference.

6. Administer the Injection

1. Choose injection site

– Common sites: abdomen (mid-line), thigh, or upper arm. Rotate sites to reduce lipodystrophy.

1. Clean the skin with an alcohol wipe.
2. Inject slowly, allowing the body to absorb the solution comfortably.
3. Post-injection care

– Massage gently if desired; avoid vigorous activity immediately after injection.

7. Storage and Shelf Life

• Store the mixed solution in a refrigerator (2–8 °C) for up to 48 hours.
• If you need longer storage, keep the individual peptides separate until just before use.
• Avoid repeated freeze-thaw cycles; each time can degrade peptide integrity.

8. Monitoring and Adjustments

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9. Precise Mixing and Dosing Instructions

1. Weighing the Vials (Optional but Recommended)

– Use a microbalance to confirm peptide concentrations; vial labels can vary slightly.

1. Step-by-Step Mixing

a. Tesmorelin

– Draw 0.004 mL from the 5 mg/2 mL vial → 10 µg.
– Transfer into a 1 mL syringe.

b. Ipamorelin
– Draw 0.04 mL from the 3 mg/1 mL vial → 40 µg.
– Transfer into another 1 mL syringe.

c. Combine both syringes into a single 2 mL syringe or small mixing container.

d. Add saline (or bacteriostatic water) to reach exactly 2 mL total volume.
– If using a 3 mL syringe, fill to the 2 mL mark after adding peptides.

1. Final Concentration

– Total dose: 50 µg.

– Volume: 2 mL → 25 µg/mL.

1. Daily Injection Schedule

| Time | Action |

|——|——–|
| 7:00 AM | Inject 1 mL of the mixed solution (contains 12.5 µg Tesmorelin + 50 µg Ipamorelin). |
| 9:00 PM | Repeat same injection to maintain steady GH stimulus. |

1. Adjusting for Individual Response

– If side effects arise, reduce the total dose by 20–30 %.

– For men plateaued performance, consider increasing the Ipamorelin proportion slightly while keeping Tesmorelin constant.

1. Safety Checkpoints

– Use a new needle for each injection.

– Dispose of needles immediately in a sharps container.
– Keep records of dates, times, and doses to track efficacy over weeks.

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10. Conclusion

By following these precise mixing and dosing steps, you can create an effective Tesmorelin/Ipamorelin blend that supports optimal growth hormone release while mitigating common side effects. Consistency in preparation, diligent monitoring, and responsible usage are key to achieving the desired results safely.